小児心臓外科手術に関連する血栓形成のリスク,臨床的特徴,結果
Cedric Manlhiot1, Ines B Menjak, Leonardo R Brandão
1The Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada M5G 1X8.
Circulation
|September 14, 2011
まとめ
小児心臓外科手術の患者は,重篤な合併症である血栓症を頻繁に発症し,回復と生存に影響を及ぼします. 早期発見と予防戦略は,これらの脆弱な子供たちのアウトカムを改善するために不可欠です.
科学分野:
- ペディアトリック・カルディオロジー
- 心血管外科手術についてです.
- トロンボシス研究研究
背景:
- 血栓症は,小児心臓外科手術の認識されていない合併症です.
- 過去の研究では,この患者集団における血栓形成に著しく焦点を当てていませんでした.
研究 の 目的:
- 心臓外科手術を受けた小児における血栓形成の発生率,危険因子,合併症,結果を調査する.
- 意識の向上と管理戦略の必要性を強調する.
主な方法:
- 1542件の小児心臓外科手術の遡及的分析.
- 444 thrombi.の特定と特徴付けについて
- リスク要因と関連する合併症を特定するための統計分析.
主要な成果:
- 患者の11%が結血栓を発症し,66%が閉塞性であり,60%が症状を発症しました.
- 危険因子には,若い年齢,低酸素飽和度,前回の血栓形成,心臓移植,深度の低熱循環停止,中央線の持続時間,体外サポートが含まれています.
- 血栓症は,ICU/入院期間,心停止,再介入,再手術,死亡率の増加と関連していました.
- トロンブの62%が長期追跡で解消し,場所とトロンブスの特徴に影響を与えました.
結論:
- 血栓症は小児心臓外科における重要な問題であり,患者のかなりの割合に影響を与えています.
- 重篤な合併症や死亡率の増加を含む有害な結果と関連しています.
- 強化された警戒,予防,および検出戦略は,このコホートにおける血栓の管理に不可欠です.
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