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Updated: May 29, 2026

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アクティブサイトグアニンは,glmSリボジームのカタリシスに,その陽子化状態で参加する

Júlia Viladoms1, Lincoln G Scott, Martha J Fedor

  • 1Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|September 23, 2011
PubMed
まとめ

この研究では,glmS ribozyme.glmSにおけるグアニン33 (G33) の触媒的役割を調査した. 結果は,G33がRNA分裂において一般的な塩基触媒ではなく,移行状態の安定剤として作用することを示している.

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