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Updated: May 29, 2026

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
07:36

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

二次性ボロンエステルのアテ複合体は,非対称合成のためのキラルな有機金属型核愛素として作用する

Robin Larouche-Gauthier1, Tim G Elford, Varinder K Aggarwal

  • 1School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.

Journal of the American Chemical Society
|September 24, 2011
PubMed
まとめ

研究者らは,ボロンエステルとアリルリチウム反応剤から新しいキラル核愛者を開発した. この方法は非対称な合成を可能にし,炭素-ボロン結合を高ステレオ制御で様々な新しい結合に変換します.

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Regioselectivity and Stereochemistry of Hydroboration

A significant aspect of hydroboration–oxidation is the regio- and stereochemical outcome of the reaction.
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Synthesis of α-Substituted Carbonyl Compounds: The Stork Enamine Reaction

α-Substituted ketones or aldehydes can be synthesized from enamines by the Stork enamine reaction, named after its pioneer Gilbert Stork. Enamines are useful synthetic intermediates where the lone pair on nitrogen is in conjugation with the C=C bond. They resemble enolate ions, as the resonance forms of both species have a nucleophilic α carbon.
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α-Alkylation of Ketones via Enolate Ions

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Hydroboration-Oxidation of Alkenes

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Alkylation of β-Ketoester Enolates: Acetoacetic Ester Synthesis

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