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単一塩基対の解き放たれと,C型肝炎ウイルスのNS3ヘリケースによる非同期的なRNAの放出

Wei Cheng1, Srikesh G Arunajadai, Jeffrey R Moffitt

  • 1Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA. chengwe@umich.edu

Science (New York, N.Y.)
|September 24, 2011
PubMed
まとめ

C型肝炎ウイルスのNS3ヘリケーゼは,2本鎖のRNAを単基対のステップで解き放ち,ATPを消費する. 新生ヌクレオチドの放出は,塩基対の開きと非同期であり,ウイルスの複製に関する洞察を提供しました.

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