関連する実験動画

Updated: May 29, 2026

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE
12:43

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE

Published on: July 29, 2014

生まれながらの免疫受容体RIG-IによるRNA認識と活性化の構造的基礎

Fuguo Jiang1, Anand Ramanathan, Matthew T Miller

  • 1Center for Advanced Biotechnology and Medicine, Department of Chemistry and Chemical Biology, Rutgers University, 679 Hoes Lane West, Piscataway, New Jersey 08854, USA.

Nature
|September 28, 2011
PubMed
まとめ

レチノ酸誘導性遺伝子I (RIG-I) は,先天的免疫を誘発するためにウイルスのRNAを認識します. その構造は,ヘリカーゼとリプレッサードメインが,抗ウイルス防御に不可欠な二重鎖RNAを結合する方法を明らかにします.

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