生まれながらの心不全および発達およびその他の精神疾患:デンマーク全国のコホート研究
Morten Olsen1, Henrik Toft Sørensen, Vibeke E Hjortdal
1Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N, Denmark. mo@dce.au.dk
Circulation
|September 28, 2011
まとめ
生まれながらの心不全 (CHD) の患者は,精神疾患のリスクが高くなります. このリスクは女性ではより高く,喘息や糖尿病などの他の疾患と比較して早期に現れる.
科学分野:
- 心臓病学 心臓病学
- 精神科医は精神病を患っている.
- 公衆衛生は公衆衛生である.
背景:
- 生まれながらの心不全 (CHD) は,心臓の発達に影響を及ぼします.
- 精神疾患は,公衆衛生上の重要な懸念事項である.
- CHDと精神疾患の関連性は,さらなる調査を必要としています.
研究 の 目的:
- 生まれながらの心不全 (CHD) を有するデンマークの患者における精神科入院と診察のリスクを調査する.
- 心臓病患者の精神病的罹患率と一般の人々の精神病的罹患率を比較する.
- 年齢,性別,その他の病状の有無に基づくリスクの潜在的差異を調査する.
主な方法:
- デンマークの全国患者登録簿とデンマーク精神科中央登録簿を利用した.
- 1977年から2002年の間に生まれた6927人のCHD患者を特定しました.
- CHD患者と10人の集団比較コホートメンバーをマッチングし,親の要因を調整しました.
主要な成果:
- 15年後,精神科の入院/診察の累積リスクは,心臓病の患者で5.9%であった.
- 精神科医の診察に対するリスク比 (HRs) は,より若いCHD患者で高かった (男性: 1.8,女性: 2.5).
- 介入や併発症に関係なく,糖尿病/喘息コホートよりも早期発症したCHD患者で精神疾患のリスクの増加が観察されました.
結論:
- 生まれながらの心臓病の患者は,発達上の問題を含む精神疾患のリスクが高まります.
- この増加したリスクは,侵襲的な治療法や他の欠陥がある場合でも,それなしでも存在します.
- これらの精神疾患の発症は,糖尿病や喘息の患者と比較して,心臓病の患者で早期に発症します.
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