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Updated: May 22, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
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酵素メチル転移:活性部位の残留が活性部位の圧縮を生成する役割は,触媒効率と相関する

Jianyu Zhang1, Judith P Klinman

  • 1Department of Chemistry, University of California, Berkeley, California 94720, USA.

Journal of the American Chemical Society
|October 1, 2011
PubMed
まとめ

ヒトカテキル-O-メチルトランスフェラーゼ (COMT) 酵素の活動は,活性部位の圧縮と関連しています. 変異は,触媒効率と動的同位体効果の間の相関を明らかにし,ドーパミンの代謝に影響を与えます.

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