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Updated: May 28, 2026

Analysis of SCAP N-glycosylation and Trafficking in Human Cells
11:27

Analysis of SCAP N-glycosylation and Trafficking in Human Cells

Published on: November 8, 2016

飽和脂肪酸は,膜サブドメイン内のc-Srcクラスタリングを誘導し,JNK活性化につながります

Ryan G Holzer1, Eek-Joong Park, Ning Li

  • 1Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

Cell
|October 4, 2011
PubMed
まとめ

飽和脂肪酸は,Jun N-末端キナーゼ (JNK) を活性化し,c-Srcタンパク質の分布を変えることで,インスリンシグナル伝達を損なう. 不飽和脂肪酸はこれを防止し,グルコース代謝に対する有益な効果のための潜在的なメカニズムを提供します.

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