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Updated: May 1, 2026

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

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CNTNAP2の欠如は,,ニューロン移動異常,および自閉症に関連するコア欠乏症につながる

Olga Peñagarikano1, Brett S Abrahams, Edward I Herman

  • 1Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

Cell
|October 4, 2011
PubMed
まとめ

Cntnap2遺伝子が欠けているマウスは,自閉症スペクトル障害 (ASD) のコア行動,発作,および異常な脳発達を示す. リスペリドン治療は,これらのCntnap2 (((-/-) マウスの繰り返し行動を改善しました.

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