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Updated: May 28, 2026

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
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Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

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大量のタンパク質ドメインの計算設計への道として対称性を探求する

Carie Fortenberry1, Elizabeth Anne Bowman, Will Proffitt

  • 1Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.

Journal of the American Chemical Society
|October 8, 2011
PubMed
まとめ

研究者は,TIM-barrel superfold を採用する対称タンパク質 (FLR) を計算的に設計した. このエンジニアリングされたタンパク質は,分裂すると,容易に安定したホモジマーを形成し,タンパク質の設計原理を前進させます.

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