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Updated: May 28, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
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補足因子Hはマロンディアルデヒドエピトープを結合し,酸化ストレスから保護する

David Weismann1, Karsten Hartvigsen, Nadine Lauer

  • 1Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.

Nature
|October 8, 2011
PubMed
まとめ

補足因子H (CFH) は,年齢関連の黄斑変性 (AMD) と関連した酸化ストレス産物であるマロンディアルデヒド (MDA) を結合する. 一般的なAMDに関連したCFH変異体は,この結合を損なっており,AMDおよび炎症性疾患の新たな治療標的を示唆しています.

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