関連する実験動画

Updated: May 10, 2026

Inducible and Reversible Dominant-negative (DN) Protein Inhibition
08:35

Inducible and Reversible Dominant-negative (DN) Protein Inhibition

Published on: January 7, 2019

競合する内生mRNAによって,腫瘍抑制剤PTENのコードから独立した調節

Yvonne Tay1, Lev Kats, Leonardo Salmena

  • 1Cancer Genetics Program, Division of Genetics, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|October 18, 2011
PubMed
まとめ

タンパク質をコードするRNAは,競合する内生RNA (ceRNAs) と呼ばれ,マイクロRNAを共有することで相互作用する. この研究では,腫瘍抑制剤PTENを調節し,がんの成長とシグナル伝達経路に影響を与えるceRNAを特定しています.

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