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Updated: May 10, 2026

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE
12:43

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE

Published on: July 29, 2014

ウイルスRNAによる先天性免疫パターン認識受容体RIG-Iの活性化のための構造的基礎

Eva Kowalinski1, Thomas Lunardi, Andrew A McCarthy

  • 1European Molecular Biology Laboratory, Grenoble Outstation, France.

Cell
|October 18, 2011
PubMed
まとめ

生まれつきの免疫に不可欠なRIG-I受容体は,インターフェロン信号伝達を活性化します. 結晶構造は,RNAとATPの結合がRIG-Iを再編成し,免疫反応のためのCARDを解放する方法を明らかにします.

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Confocal Imaging of Double-Stranded RNA and Pattern Recognition Receptors in Negative-Sense RNA Virus Infection

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