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Mre11とExo1によるDNA二重鎖断裂の双方向解切

Valerie Garcia1, Sarah E L Phelps, Stephen Gray

  • 1Genome Damage and Stability Centre, The University of Sussex, Brighton, BN1 9RQ, UK.

Nature
|October 18, 2011
PubMed
まとめ

この研究は,Mre11外核酵素が,双方向切除を可能にすることで,DNA二重鎖破裂修復に重要な役割を果たしていることを明らかにしています. このプロセスは,効率的なDNA修復に不可欠であり,DNA損傷に対する耐性を授与します.

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