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Updated: May 28, 2026

Enrichment of Bacterial Lipoproteins and Preparation of N-terminal Lipopeptides for Structural Determination by Mass Spectrometry
10:59

Enrichment of Bacterial Lipoproteins and Preparation of N-terminal Lipopeptides for Structural Determination by Mass Spectrometry

Published on: May 21, 2018

ハロドラシンαはペプチドグリカン前駆体である脂質IIを2:1ステキオメトリーで結合する

Trent J Oman1, Tania J Lupoli, Tsung-Shing Andrew Wang

  • 1Department of Chemistry, University of Illinois, 600 South Mathews Avenue, Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|October 19, 2011
PubMed
まとめ

ハルαとハルβペプチドから成るランチビオティックハロドゥラシンは,細菌の細胞壁合成を阻害する. ハラαは,脂質IIに結合することで,重要な酵素を特定的にブロックし,細菌の死につながります.

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