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Updated: May 28, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
06:46

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

アルデヒドのホモアリルボレーションとホモクロチルボレーション

Wenbo Pei1, Isaac J Krauss

  • 1Department of Chemistry MS 015, Brandeis University, Waltham, Massachusetts 02454-9110, USA.

Journal of the American Chemical Society
|October 22, 2011
PubMed
まとめ

新しいサイクロプロパネートアリルボレーション法では,アルデヒドにホモアリル断片を効率的に加え,ビショモアリルアルコールを生成します. この反応は,メチル置換製品に対して高いステレオ選択性を提供し,有機合成に有用である.

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Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation

Introduction
One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
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Aldehydes and Ketones with Alcohols: Hemiacetal Formation

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C–C Bond Formation: Aldol Condensation Overview

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Acid-Catalyzed α-Halogenation of Aldehydes and Ketones

By replacing an α-hydrogen with a halogen, acid-catalyzed α-halogenation of aldehydes or ketones yields a monohalogenated product
In the first step of the mechanism, the acid protonates the carbonyl oxygen resulting in a resonance-stabilized cation, which subsequently loses an α-hydrogen to form an enol tautomer. The C=C bond in an enol is highly nucleophilic because of the electron-donating nature of the –OH group. Consequently, the double bond attacks an electrophilic halogen to form a...
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Aldehydes and ketones are prepared from alcohols, alkenes, and alkynes via different reaction pathways. Alcohols are the most commonly used substrates for synthesizing aldehydes and ketones. The conversion of alcohol to aldehyde, which involves the oxidation process, depends on the class of the alcohol used and the strength of the oxidizing agent. For instance, primary alcohol will form an aldehyde when treated with a weak oxidizing agent; however, it gets over-oxidized to a carboxylic acid in...
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Base-Catalyzed Aldol Addition Reaction

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