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Updated: May 28, 2026

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
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Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

エンドオカンナビノイドの水解により,神経炎症を促進する脳プロスタグランディンが生成されます

Daniel K Nomura1, Bradley E Morrison, Jacqueline L Blankman

  • 1The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. dnomura@berkeley.edu

Science (New York, N.Y.)
|October 25, 2011
PubMed
まとめ

モノアシルグリセロールリパゼ (MAGL) は,異なる経路を通じて脳プロスタグランディンを生成し,パーキンソン病のモデルで神経保護を提供します. MAGLの阻害は,神経変性疾患のより安全な治療戦略を提供する可能性があります.

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