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Updated: May 28, 2026

Detection of the pH-dependent Activity of Escherichia coli Chaperone HdeB In Vitro and In Vivo
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Published on: October 23, 2016

HdeAジメルのpH依存解離を検知する

Bin W Zhang1, Lucia Brunetti, Charles L Brooks

  • 1Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, Michigan 48109, USA.

Journal of the American Chemical Society
|October 27, 2011
PubMed
まとめ

HdeAチャペロンタンパク質は,酸性条件下でモノマーに分解し,タンパク質の集積を防止します. 分子ダイナミクスのシミュレーションにより,このpHに依存した解離とチャペロン機能を駆動する主要な残留相互作用が明らかになりました.

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