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Updated: May 28, 2026

High-throughput Yeast Plasmid Overexpression Screen
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酵母菌におけるAβ毒性,内細胞密輸,アルツハイマー病の危険因子との機能的関連

Sebastian Treusch1, Shusei Hamamichi, Jessica L Goodman

  • 1Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|October 29, 2011
PubMed
まとめ

アルツハイマー病 (AD) の重要な要因であるβ-アミロイドペプチド (Aβ) 毒性は,酵母で研究されました. 研究者らは,酵母,ワーム,ネズミの神経細胞におけるAβ毒性を修正する新しい内細胞経路因子を特定しました.

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