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成人期における適度なアルコール摂取,飲酒習慣,乳がんのリスク
Wendy Y Chen1, Bernard Rosner, Susan E Hankinson
1Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA. wendy.chen@channing.harvard.edu
JAMA
|November 3, 2011
まとめ
アルコール摂取量が少ない場合でも,乳がんのリスクが高くなりますが,特に飲酒乱用のパターンが多い場合は特にそうです. 成人期にわたる累積的なアルコール摂取は,いつ発生したかにかかわらず,重要な要因です.
科学分野:
- エピデミオロジー エピデミオロジー
- 公衆衛生は公衆衛生である.
- 腫瘍学 腫瘍学
背景:
- アルコール摂取と乳がんのリスクの増加との関連が証明された.
- 低アルコール摂取量に関連するリスクの限られた定量化.
- 成人期における飲酒パターンと消費のタイミングの不明な影響.
研究 の 目的:
- 乳がんと成人の生涯におけるアルコール摂取量との関係を評価する.
- アルコールの量,飲酒頻度,および飲酒年齢が乳がんリスクに及ぼす影響を分析する.
- 低レベルのアルコール消費に関連するリスクを定量化するために.
主な方法:
- 看護師の健康研究 (1980-2008) の女性105,986人を含む見通し観察研究.
- 早期の成人アルコール評価と,フォローアップ期間中に8つの更新された評価を使用しました.
- 侵襲性乳がんを発症する相対リスクのモニタリング.
主要な成果:
- 乳がんのリスクの統計的に有意な増加は,低消費レベル (5.0〜9.9g/日) でさえ観察されました.
- 累積摂取量に関係なく,過度の飲酒は,乳がんのリスクの増加と関連していました.
- 成人期の早期と後期の両方でアルコールの消費は,独立してリスクの増加に寄与しました.
結論:
- 低アルコール摂取は,乳がんリスクのわずかな増加と関連しています.
- 成人期にわたる累積的なアルコール摂取は,乳がんの有意な予測因子です.
- 人生のさまざまな段階でのアルコールの消費は,乳がんのリスクに影響を及ぼします.
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