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Updated: May 27, 2026

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

触媒制御型ステレオ選択型環閉メタテシスによるマクロサイクリックな天然産物の合成

Miao Yu1, Chenbo Wang, Andrew F Kyle

  • 1Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, USA.

Nature
|November 5, 2011
PubMed
まとめ

この研究では,アルケンの立体化学を正確に制御するリングクロージングメタテシス (RCM) のための新しいボルンガムベースの触媒を導入しています. このブレークスルーにより,複雑なマクロサイクルの分子の高度にステレオ選択的合成が可能になり,天然製品の合成が改善されます.

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