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ヒストン mRNA 3' 末端処理には,スレオニン-4 にリン酸化された RNAP II CTD が必要です

Jing-Ping Hsin1, Amit Sheth, James L Manley

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

Science (New York, N.Y.)
|November 5, 2011
PubMed
まとめ

RNAポリメラーゼIIC端末領域 (CTD) Thr(4) のリン酸化はヒストンのmRNA処理に不可欠である. CDK9を必要とするこの改変は,効率的な遺伝子発現のためにヒストン遺伝子の処理因子を採用するのに役立ちます.

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