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Updated: May 27, 2026

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let-7マイクロRNAとLin28との相互作用の分子基礎である

Yunsun Nam1, Casandra Chen, Richard I Gregory

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|November 15, 2011
PubMed
まとめ

Lin28タンパク質は,特にlet-7の前駆体と結合することによって,let-7マイクロRNA (miRNA) 産生を抑制する. その構造は,それが多様なlet-7ファミリーメンバーを認識する方法を明らかにし,遺伝子発現における規制的な役割を説明します.

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