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Updated: May 27, 2026

Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator
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Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

アディポサイトNCoRノックアウトはPPARγのリン酸化を低下させ,PPARγの活性とインスリン感受性を高めます

Pingping Li1, Wuqiang Fan, Jianfeng Xu

  • 1Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

Cell
|November 15, 2011
PubMed
まとめ

脂肪細胞における核受容体コアプレッサー (NCoR) のノックアウトは,肥満マウスのグルコース耐性およびインスリン感受性を改善する. NCoRを削除すると,炎症を軽減し,脂肪細胞の機能を高め,糖尿病薬の効果を模倣します.

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