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Updated: May 27, 2026

Nanomanipulation of Single RNA Molecules by Optical Tweezers
06:59

Nanomanipulation of Single RNA Molecules by Optical Tweezers

Published on: August 20, 2014

イオンジャンプと温度抑制シミュレーションを用いたヒトテロメラーゼRNAシドオノットの折り畳み

Shi Biyun1, Samuel S Cho, D Thirumalai

  • 1Biophysics Program, Institute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742, USA.

Journal of the American Chemical Society
|November 16, 2011
PubMed
まとめ

RNAの折り畳みは複雑で,複数の経路を含む. 分子シミュレーションでは,ヒトテロメラーゼRNA (hTR) は熱力学的に2つの状態のシステムであるように見えますが,その折り畳み運動は複雑で並列の経路と初期条件が崩壊ダイナミクスを大きく影響することを明らかにしています.

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