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Updated: May 27, 2026

Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability
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Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability

Published on: February 3, 2022

クロトナース触媒は,機能化されたプロリンとカルバペナムの柔軟な生産を可能にします

Refaat B Hamed1, Luc Henry, J Ruben Gomez-Castellanos

  • 1Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom.

Journal of the American Chemical Society
|November 19, 2011
PubMed
まとめ

エンジニアリングされた酵素は,機能化されたプロリン誘導体とバイサイクルベータ-ラクタムを作り出します. このバイオカタリシスは,ステレオ選択合成を進めて,四次中心を持つ複雑な分子を生成します.

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