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Updated: May 27, 2026

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling
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Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling

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バクテリアのインドルシグナル伝達を,フルーストラミン誘導体で遮断する

Cynthia A Bunders1, Marine J Minvielle, Roberta J Worthington

  • 1Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, USA.

Journal of the American Chemical Society
|November 19, 2011
PubMed
まとめ

新しいデスフォーミルフルーストラブロミン (dFBr) 誘導体は,インドルシグナリングを調節することにより,細菌のバイオフィルム形成を効果的に抑制します. これらの化合物は,インドールと比較して,著しく活性化され,病原性細菌を制御するための有望な戦略を提供します.

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