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Updated: May 26, 2026

Reconstruction of the Blood-Brain Barrier In Vitro to Model and Therapeutically Target Neurological Disease
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ヘッジホッグ経路は,血脳バリアの整合性と中枢神経系の免疫静止を促進します

Jorge Ivan Alvarez1, Aurore Dodelet-Devillers, Hania Kebir

  • 1Neuroimmunology Unit, Center of Excellence in Neuromics, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Faculty of Medicine, Université de Montréal, Montréal, Quebec, Canada.

Science (New York, N.Y.)
|December 7, 2011
PubMed
まとめ

アストロサイトと内皮細胞を含むヘッジホッグ (Hh) 信号伝達経路は,血脳障壁 (BBB) の維持に不可欠です. この経路はまた,BBBの炎症と免疫細胞活動を抑制します.

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