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Updated: May 26, 2026

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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コファクター結合は,ホックスタンパク質間のDNA結合特異性の潜在的差異を誘発する

Matthew Slattery1, Todd Riley, Peng Liu

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, 701 West 168(th) Street, HHSC 1104, New York, NY 10032, USA.

Cell
|December 14, 2011
PubMed
まとめ

転写因子は,コファクターとの複合体を形成する際に,新しいDNA結合能力を獲得する. この研究は,ドロソフィラホックスタンパク質が,Extradenticle-Homothoraxコファクターで認識特性をどのように変化させるかを明らかにしています.

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