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Updated: May 26, 2026

In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity
09:45

In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity

Published on: January 29, 2018

Myc駆動型腫瘍発生には,SUMOylationに依存した転写サブプログラムが必要です

Jessica D Kessler1, Kristopher T Kahle, Tingting Sun

  • 1Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.

Science (New York, N.Y.)
|December 14, 2011
PubMed
まとめ

SUMO活性化酵素 (SAE1/2) を標的にすることは,Myc駆動がんにおける合成致死性を引き起こします. SAE1/2を阻害すると,Myccが破壊される.

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SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer08:29

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer

Published on: November 1, 2019

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