TALDNA

Dong Deng1, Chuangye Yan, Xiaojing Pan

  • 1State Key Laboratory of Bio-Membrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China.

Science (New York, N.Y.)
|January 7, 2012
PubMed
まとめ

トランスクリプションアクティベーター型 (TAL) エフェクターは,繰り返しドメインを使用してDNAを結合します. 結晶構造は,TALエフェクターが特定のDNA配列を,その反復変数残基 (RVDs) を通して認識し,タンパク質の設計を支援する方法を明らかにします.

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