化学霊長類:胚性幹細胞は適用する必要はありません
Alan Trounson1, Uta Grieshammer
1California Institute for Regenerative Medicine, 210 King Street, San Francisco, CA 94107, USA. atrounson@cirm.ca.gov
Cell
|January 10, 2012
まとめ
研究者たちは,最初のレサス猿のキメラを作った. 非ヒトの霊長類のキメラの生成におけるこの画期的な進歩は,4細胞の胚を集約することによって達成されましたが,胚性幹細胞を注入することによってではありません.
科学分野:
- 発達生物学 発達生物学とは
- 靈長類の研究は,霊長類の研究である.
- 幹細胞生物学 幹細胞生物学とは
背景:
- 生存可能なキメラを生成することは,早期発達と疾患モデリングの研究に不可欠です.
- 胚性幹細胞を用いた非人間霊長類のキメラを作成する以前の試みは失敗した.
- マウスのキメラは,胚性幹細胞をブラストキスタに注入することによって,定期的に生成されます.
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