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Updated: May 19, 2026

Single Molecule Fluorescence Microscopy on Planar Supported Bilayers
20:00

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タンパク質のトランスメブラン領域による単一のスフィンゴリピド種の分子認識

F-Xabier Contreras1, Andreas M Ernst, Per Haberkant

  • 1Heidelberg University Biochemistry Center, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany.

Nature
|January 11, 2012
PubMed
まとめ

この研究では,特定のスフィンゴミエリン (SM18) がp24タンパク質のトランスメブラン領域に直接結合し,その活性とCOPI依存の輸送を調節することを明らかにしました. これは,スフィンゴリピドが膜タンパク質機能の重要なコファクターであることを強調しています.

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