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Updated: Mar 31, 2026

Comparative Lesions Analysis Through a Targeted Sequencing Approach
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Comparative Lesions Analysis Through a Targeted Sequencing Approach

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再発性急性骨髄性白血病におけるクローン進化は,全ゲノム配列決定により明らかになりました

Li Ding1, Timothy J Ley, David E Larson

  • 1The Genome Institute, Washington University, St Louis, Missouri 63108, USA.

Nature
|January 13, 2012
PubMed
まとめ

急性骨髄性白血病 (AML) の再発は,新しい突然変異とクローン進化を伴う. 化学療法がこれらの変化を誘発する可能性があるのは,創業クローンがしばしば持続し,追加の変異を身に付けるためだ.

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