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Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
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Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

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ダイナミックレンジを拡張,縮小,または任意に編集したエンジニアリングバイオセンサ.

Alexis Vallée-Bélisle1, Francesco Ricci, Kevin W Plaxco

  • 1Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.

Journal of the American Chemical Society
|January 14, 2012
PubMed
まとめ

研究者は,幅広い標的濃度検出の限界を克服するために,人工バイオセンサを設計しました. 自然の戦略を適応することによって,より広範なアプリケーションのために,これらのバイオセンサのダイナミックレンジを成功裏に拡張し,精製しました.

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Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...