2'-ヒドロキシルのRNAの構成的異質性への固有の貢献

Elizabeth J Denning1, Alexander D MacKerell

  • 1Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, USA.

まとめ

RNA 2'-ヒドロキシルグループは,RNA構造を制御する分子スイッチとして作用します. その方向性は,RNAが正規のA型を採用するか,あるいは様々な非正規の形状を探求するかを決定する.

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RNA Stability01:53

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Intact DNA strands can be found in fossils, while scientists sometimes struggle to keep RNA intact under laboratory conditions. The structural variations between RNA and DNA underlie the differences in their stability and longevity. Because DNA is double-stranded, it is inherently more stable. The single-stranded structure of RNA is less stable but also more flexible and can form weak internal bonds. Additionally, most RNAs in the cell are relatively short, while DNA can be up to 250 million...
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Different Types of RNA Have the Same Basic Structure
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RNA Structure01:23

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Overview
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Different Types of RNA Have the Same Basic Structure
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