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ガレクチン8は,損傷した膀をオートファギーの標的とし,細胞をバクテリアの侵入から守ります

Teresa L M Thurston1, Michal P Wandel, Natalia von Muhlinen

  • 1MRC Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Hills Road, Cambridge CB2 0QH, UK.

Nature
|January 17, 2012
PubMed
まとめ

ガレクチン8は,細胞の危険受容体として作用し,セルラー小胞に損傷を検知することで,サルモネッラなどの侵入細菌を識別します. これは,病原体を排除するための細胞防衛機構であるオートファギーを開始します.

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