関連する実験動画

Updated: Jan 8, 2026

Author Spotlight: Exploring Heat Shock Proteins in Malaria and Tuberculosis Infections
07:14

Author Spotlight: Exploring Heat Shock Proteins in Malaria and Tuberculosis Infections

Published on: March 8, 2024

1.9K

E. coliのDNA結合タンパク質HUは,円形の二重鎖DNAを持つ核細胞のような構造を形成する.

J Rouvière-Yaniv, M Yaniv, J E Germond

    Cell
    |June 1, 1979
    PubMed
    まとめ

    E. coliのDNA結合タンパク質HUはDNAを圧縮し,超螺旋的な回転を導入し,ビーズ状の構造を形成します. これらのDNA-HU複合体はクロマチンに似ており,DNA組織における役割を示唆しています.

    さらに関連する動画

    Analyzing and Building Nucleic Acid Structures with 3DNA16:24

    Analyzing and Building Nucleic Acid Structures with 3DNA

    Published on: April 26, 2013

    21.2K
    Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes11:42

    Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

    Published on: November 1, 2012

    10.3K

    関連する概念動画

    Genomic DNA in Prokaryotes00:46

    Genomic DNA in Prokaryotes

    The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
    Genomic Diversity in Bacteria
    Although bacterial genomes are much...
    48.2K
    Genomic DNA in Eukaryotes00:58

    Genomic DNA in Eukaryotes

    Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
    52.1K
    Single-Strand DNA Binding Proteins01:03

    Single-Strand DNA Binding Proteins

    For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
    16.4K
    The Nucleosome Core Particle02:10

    The Nucleosome Core Particle

    Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
    The paradox
    Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
    14.0K
    The Nucleosome Core Particle01:12

    The Nucleosome Core Particle

    Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
    Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their primary aim is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. On the other hand, they must allow polymerase enzymes to access histone-bound DNA during...
    2.1K
    The Nucleosome01:19

    The Nucleosome

    Human DNA is almost two meters long. However, it is compressed inside a tiny nucleus measuring only a few microns in diameter. To make this degree of compaction possible, DNA is organized into several sequential levels so that it can fit into such a tiny space. The most compact form of DNA is a chromosome that can be seen under a microscope in a dividing cell.
    In a chromosome, DNA is wound twice around a protein complex called a histone octamer core, which consists of 8 histone proteins. This...
    3.6K