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Updated: Jun 26, 2026

Using the E1A Minigene Tool to Study mRNA Splicing Changes
10:25

Using the E1A Minigene Tool to Study mRNA Splicing Changes

Published on: April 22, 2021

エクソン突然変異は,U1 snRNAペアリングから5'スプライスサイト選択を切り離す

B Séraphin1, M Rosbash

  • 1Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusetts 02254.

Cell
|November 2, 1990
PubMed
まとめ

イーストのスプライスサイト変異は,機能的なスプライスサイトを作り,異常なmRNAの翻訳を可能にします. これは,保存されたイントロンGが,U1 snRNAのペアリングとは独立して,スプライシングに不可欠であることを示唆しています.

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