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Updated: May 12, 2026

Chromatin Interaction Analysis with Paired-End Tag Sequencing (ChIA-PET) for Mapping Chromatin Interactions and Understanding Transcription Regulation
21:55

Chromatin Interaction Analysis with Paired-End Tag Sequencing (ChIA-PET) for Mapping Chromatin Interactions and Understanding Transcription Regulation

Published on: April 30, 2012

広範囲にわたるプロモーター中心のクロマチンの相互作用は,転写調節のためのトポロジカルな基礎を提供します

Guoliang Li1, Xiaoan Ruan, Raymond K Auerbach

  • 1Genome Institute of Singapore, Singapore 138672, Republic of Singapore.

Cell
|January 24, 2012
PubMed
まとめ

この研究では,ペアリング・エンド・タグ配列化 (ChIA-PET) によるクロマチンの相互作用分析を用いてマッピングされた上位階のクロマチンの相互作用が,ヒト細胞における遺伝子転写を調節し,一般的および特異的な遺伝子活動の両方に影響を与えることを明らかにしています.

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