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Updated: Jan 27, 2026

Preparation and Reactivity of Gasless Nanostructured Energetic Materials
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ΔF508 CFTRの折りたたみと機能を回復するために,NBD1のエネルギーとドメインインタフェースの両方の修正が必要です

Wael M Rabeh1, Florian Bossard, Haijin Xu

  • 1Department of Physiology, McGill University, Montréal, Quebec H3E 1Y6, Canada.

Cell
|January 24, 2012
PubMed
まとめ

胞性線維症のトランスメブラン伝導性調節器 (CFTR) の誤折れを修正するには,NBD1ドメインのエネルギーとNBD1-MSD2インターフェースの両方を安定させる必要があります. この二重アプローチは,CFTRタンパク質の機能と輸送の回復に不可欠です.

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