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Updated: May 25, 2026

Spectral Karyotyping to Study Chromosome Abnormalities in Humans and Mice with Polycystic Kidney Disease
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Published on: February 3, 2012

Kelch-like 3 と cullin 3 の変異は高血圧と電解質異常を引き起こす

Lynn M Boyden1, Murim Choi, Keith A Choate

  • 1Department of Genetics and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

Nature
|January 24, 2012
PubMed
まとめ

KLHL3またはCUL3遺伝子の変異は,高血圧症候群であるPHAII型偽ホイポアルドステロン症を引き起こす. これらの遺伝子は,血圧と電解質バランスのために不可欠であり,チアジド性尿薬によって病気の特徴が逆転します.

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