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Updated: May 25, 2026

A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates
11:49

A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates

Published on: August 21, 2018

合理的に設計されたピロリシル-tRNA合成酵素変異体で,基板のスペクトルが広い

Yane-Shih Wang1, Xinqiang Fang, Ashley L Wallace

  • 1Department of Chemistry, Texas A&M University, College Station, Texas 77843, USA.

Journal of the American Chemical Society
|February 1, 2012
PubMed
まとめ

研究者らは,新しいフェニララニン誘導体を設計された酵素とtRNAを使用してタンパク質に遺伝的に組み込みました. これは,E. coli. の新しいアミノ酸でタンパク質を作成するためのツールキットを拡張します.

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