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Updated: May 25, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
08:09

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale

Published on: April 19, 2021

タンパク質におけるミリ秒交換ダイナミクスを,サイドチェーン1Hプローブを用いたCPMGリラクゼーション分散型NMRによって定量化

Alexandar L Hansen1, Patrik Lundström, Algirdas Velyvis

  • 1Department of Molecular Genetics, The University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Journal of the American Chemical Society
|February 4, 2012
PubMed
まとめ

この研究は,標識されたタンパク質を使用して,タンパク質のサイドチェーンにおけるミリ秒間の化学交換を測定するための新しい方法を導入しています. この技術は,以前の限界を克服し,タンパク質動力のより詳細な構造研究を可能にします.

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