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Updated: Feb 3, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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抑制性表 epithelial 環境から単一の腫瘍遺伝子を発現する細胞の成長

Cheuk T Leung1, Joan S Brugge

  • 1Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|February 10, 2012
PubMed
まとめ

単細胞における腫瘍遺伝子の活性化は,腫瘍の成長を誘発する. ERBB2の過剰発現は細胞の移動と増殖を誘発し,乳腺アシニにおけるクローン選択と腫瘍の進行を促します.

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