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Updated: May 25, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

2つの別々の遺伝子クラスターは,アスペルギルス・ニドゥランス (Aspergillus nidulans) のメロテルペノイド・オースチンノール (austinol) とデヒドロアースチンノール (dehydroaustinol)

Hsien-Chun Lo1, Ruth Entwistle, Chun-Jun Guo

  • 1Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, 1985 Zonal Avenue, Los Angeles, California 90089, United States.

Journal of the American Chemical Society
|February 15, 2012
PubMed
まとめ

驚くべきことに,アスペルギルスニドゥランスの2つの別々の遺伝子クラスターは,真菌のメロテルペノイド生物合成に必要である. この研究は,完全な生物合成経路を明らかにし,新しい化合物と中間物質を特定します.

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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

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