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Updated: May 24, 2026

Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer
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Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer

Published on: April 13, 2015

抗テロメラーゼ治療は,ALTとミトコンドリアの適応メカニズムをがんに誘発する

Jian Hu1, Soyoon Sarah Hwang, Marc Liesa

  • 1Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Cell
|February 21, 2012
PubMed
まとめ

T細胞リンパ腫におけるテロメラーゼの抑制は,テロメア (ALT) の代替延長を通じてがん適応につながる可能性があります. PGC-1βのようなALT経路をターゲットにすると,テロメラーゼ抑制とともに,がん治療を改善する可能性があります.

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Telomerase Activity in the Various Regions of Mouse Brain: Non-Radioactive Telomerase Repeat Amplification Protocol (TRAP) Assay10:14

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