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Updated: May 20, 2026

Examining Proteasome Assembly with Recombinant Archaeal Proteasomes and Nondenaturing PAGE: The Case for a Combined Approach
09:57

Examining Proteasome Assembly with Recombinant Archaeal Proteasomes and Nondenaturing PAGE: The Case for a Combined Approach

Published on: December 17, 2016

免疫性および構成性プロテアゾームの結晶構造は,基板および阻害剤特異性の違いを明らかにします

Eva M Huber1, Michael Basler, Ricarda Schwab

  • 1Center for Integrated Protein Science at the Department Chemie, Lehrstuhl für Biochemie, Technische Universität München, Garching D-85747, Germany.

Cell
|February 21, 2012
PubMed
まとめ

マウスのプロテアソームと免疫プロテアソームの構造を決定し,抑制剤PR-957が免疫プロテアソームをどのように選択的に標的としているかを明らかにしました. この発見は,がんや自己免疫疾患に対する新薬の設計に役立ちます.

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A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

The Determination of Protease Specificity in Mouse Tissue Extracts by MALDI-TOF Mass Spectrometry: Manipulating PH to Cause Specificity Changes09:47

The Determination of Protease Specificity in Mouse Tissue Extracts by MALDI-TOF Mass Spectrometry: Manipulating PH to Cause Specificity Changes

Published on: May 25, 2018

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