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Updated: May 24, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
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TLR5-フラゲリン認識とシグナリングの構造的基礎

Sung-il Yoon1, Oleg Kurnasov, Venkatesh Natarajan

  • 1Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|February 21, 2012
PubMed
まとめ

トール型受容体5 (TLR5) はバクテリアのフラゲリンと結合し,免疫反応を開始します. この研究は,斑馬魚TLR5がフラゲリンと複合した原子構造を明らかにし,シグナル伝達複合体をどのように形成するのかを詳細に説明しています.

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