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Updated: May 24, 2026

Real-Time Monitoring of Aurora kinase A Activation using Conformational FRET Biosensors in Live Cells
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Published on: July 30, 2020

合成アダプタタンパク質でキナーゼ特異性を再配線する

Elissa M Hobert1, Alanna Schepartz

  • 1Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, USA.

Journal of the American Chemical Society
|February 23, 2012
PubMed
まとめ

ミニチュアタンパク質から作られた合成アダプタータンパク質は,細胞の信号伝達経路をリダイレクトすることができます. この研究では,特定のキナーゼによってp53調節体のチロシンリン酸化を誘導する新しいアダプタが実証されました.

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